International Collaborative for Drug Stability Testing

A BSAC initiative

Resources

Open access publications and stability testing data can be accessed below.

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Piperacillin tazobactam stability antimicrobial United Kingdom
Stability of piperacillin / tazobactam 56.9mg/ml in sodium chloride 0.9%
Author:  Daniel Simms
Country:  United Kingdom
Drug stability study
piperacillin tazobactam stability antibiotic United Kingdom
Stability of piperacillin / tazobactam 56.9mg/ml in glucose 5%
Author:  Daniel Simms
Country:  United Kingdom
Drug stability study
clindamycin antibiotic stability United Kingdom
Stability of clindamycin 9.52mg/ml in glucose 5%
Author:  Daniel Simms
Country:  United Kingdom
Drug stability study
clindamycin stability antibiotic United Kingdom
Stability of clindamycin 9.52mg/ml in sodium chloride 0.9%
Author:  Daniel Simms
Country:  United Kingdom
Drug stability study
United Kingdom
PUBLISHED MANUSCRIPT: Assessment of the stability of citrate-buffered piperacillin/tazobactam for continuous infusion when stored in two commercially available elastomeric devices for outpatient parenteral antimicrobial chemotherapy: a study compliant with the NHS Yellow Cover Document requirements.
Author:  Conor Jamieson, Laima Ozolina, R Andrew Seaton, Mark Gilchrist, Tim Hills, Felicity Drummond, Alan-Shaun Wilkinson, on behalf of the BSAC Drug Stability Testing Working Group
Country:  United Kingdom
European Journal of Hospital Pharmacy online (http:// dx. doi. org/ 10. 1136/ ejhpharm- 2020- 002340)
Investigation Compliance Outpatient Influence Stability Meropenem United Kingdom
PUBLISHED MANUSCRIPT: Investigation of meropenem stability after reconstitution: the influence of buffering and challenges to meet the NHS Yellow Cover Document compliance for continuous infusions in an outpatient setting
Author:  Conor Jamieson, Michael Charles Allwood, Donata Stonkute, Andrew Wallace, Alan-Shaun Wilkinson, Tim Hills, on behalf of the BSAC Drug Stability Working Party
Country:  United Kingdom
European Journal of Hospital online (http: 2018;0:1–5. doi:10.1136/ejhpharm-2018-001699)
Stability Flucloxacillin United Kingdom
PUBLISHED MANUSCRIPT: Assessment of the stability of citrate-buffered flucloxacillin for injection when stored in two commercially available ambulatory elastomeric devices: INfusor LV (Baxter) and Accufuser (Woo Young Medical): a study compliant with the NHS Yellow Cover Document (YCD) requirements.
Author:  Michael Charles Allwood, Donata Stonkute, Andrew Wallace, Alan-Shaun Wilkinson, Tim Hills, and Conor Jamieson on behalf of the BSAC Drug Stability Working Party
Country:  United Kingdom
European Journal of Hospital online (http: 2018. 0:1–5. doi:10.1136/ejhpharm-2018-001515)
Stability Antimicrobial United Kingdom
PUBLISHED MANUSCRIPT: Extended stability of antimicrobial agents in administration devices
Author:  Abi Jenkins; Tim Hills; Mark Santillo; Mark Gilchrist; Journal of Antimicrobial Chemotherapy 2017; doi: 10.1093/jac/dkw556
Country:  United Kingdom
United Kingdom
POSTER: Cefatzidime
Author:  Conor Jamieson, Felicity Drummond, Laima Ozolina and Alan-Shaun Wilkinson, on behalf of the UK OPAT Initiative Drug and Stability Working Group
Country:  United Kingdom
Title: Stability testing of ceftazidime solutions for injection in elastomeric devices at 12 mg/mL and 25 mg/mL in 0.9% w/v saline for safe use in Outpatient Parenteral Antimicrobial Therapy (OPAT). Presented at the BSAC OPAT Conference, 11 December 2019.
United Kingdom
POSTER: Ceftolozane/tazobactam
Author:  Conor Jamieson, Felicity Drummond, Laima Ozolina and Alan-Shaun Wilkinson, on behalf of the UK OPAT Initiative Drug and Stability Working Group
Country:  United Kingdom
Title: Assessing the stability of ceftolozane/tazobactam (ZERBAXA®) at 5 mg/mL and 20 mg/mL following reconstitution and dilution in 0.9% saline in two commercially available elastomeric devices. Presented at the BSAC OPAT Conference, 11 December 2019.
United Kingdom
POSTER: Piperacillin/tazobactam
Author:  Conor Jamieson, Felicity Drummond, Laima Ozolina and Alan-Shaun Wilkinson, on behalf of the UK OPAT Initiative Drug and Stability Working Group
Country:  United Kingdom
Title: Assessing the stability of piperacillin/tazobactam at 25 mg/mL and 90 mg/mL reconstituted and diluted in 0.3% w/v citrate buffered saline in two commercially available elastomeric devices. Presented at the BSAC OPAT Conference,11 December 2019.
United Kingdom
POSTER: OPAT flow rate
Author:  Tim Hills, Conor Jamieson, Mark Gilchrist, Carolyne Horner, Andrew Seaton, on behalf of the UK OPAT Initiative Drug and Stability Working Group
Country:  United Kingdom
Title: Outcomes of a National Survey of Experience with Continuous Infusion Elastomeric Devices in OPAT. Presented at the BSAC OPAT Conference, 13-14th December 2018.
United Kingdom
POSTER: Flucloxacillin
Author:  Tim Hills MRPharmS Michael Charles Allwood PhD, Donata Stonkute BSc, Andrew Wallace PhD, Alan-Shaun Wilkinson PhD, on behalf of the BSAC Drug Stability Working Party.
Country:  United Kingdom
Title: Assessment of the stability of citrate-buffered Flucloxacillin for injection when stored in two commercially available ambulatory devices: INfusor (Baxter) and Accufuser® (Woo Young Medical), a study compliant with the NHS Yellow Cover Document (YCD) requirements. Presented at the BSAC OPAT Conference, 11-12th December 2017.
United Kingdom
POSTER: Meropenem
Author:  Tim Hills MRPharmS Michael Charles Allwood PhD, Donata Stonkute BSc, Andrew Wallace PhD, Alan-Shaun Wilkinson PhD, on behalf of the BSAC Drug Stability Working Party.
Country:  United Kingdom
The influence of pH and buffering on the stability of Meropenem 6.25-25 mg/ml at 32C. Presented at the BSAC OPAT Conference, 11-12th December 2017.
United Kingdom
DOCUMENT: OPAT Guidance
Author:  Mark Santillo, Abi Jenkins, Conor Jamieson on behalf of the NHS Pharmaceutical Quality Assurance Committee.
Country:  United Kingdom
Guidance on the pharmaceutical issues concerning OPAT Services and other outpatient intravenous therapies
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